Genetic mechanisms that underlie epilepsy

@article{Steinlein2004GeneticMT,
  title={Genetic mechanisms that underlie epilepsy},
  author={Ortrud K Steinlein},
  journal={Nature Reviews Neuroscience},
  year={2004},
  volume={5},
  pages={400-408}
}
Genetic factors can cause recurrent abnormal synchronization and episodic hyperexcitability of neuronal networks through various mechanisms. Many of the genes that have been implicated in idiopathic epilepsies code for ion channels, whereas syndromes with epilepsy as a main feature are caused by genes that are involved in functions as diverse as cortical… CONTINUE READING