Genetic markers and the majority's right not to know

@article{Appel2004GeneticMA,
  title={Genetic markers and the majority's right not to know},
  author={J. Appel and J. Friedman},
  journal={Movement Disorders},
  year={2004},
  volume={19}
}
  • J. Appel, J. Friedman
  • Published 2004
  • Medicine
  • Movement Disorders
  • Ethical issues frequently arise in the study of genetic disorders, particularly autosomal dominant diseases for which gene testing is commercially available. We wish to discuss a problem that arose in a study of Machado Joseph disease (MJD, spinocerebellar ataxia type 3, SCA 3) by Friedman et al.1 One of the authors (J.H.F.) observed that 5 of 6 patients with genetically confirmed MJD also described symptoms suggestive of REM sleep behavior disorder (RBD).2 One patient described RBDsuggestive… CONTINUE READING

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