Genetic mapping with SNP markers in Drosophila

  title={Genetic mapping with SNP markers in Drosophila},
  author={J{\"u}rg Berger and Takashi Suzuki and K Senti and Janine Stubbs and Gotthold Schaffner and Barry J. Dickson},
  journal={Nature Genetics},
Map-based positional cloning of Drosophila melanogaster genes is hampered by both the time-consuming, error-prone nature of traditional methods for genetic mapping and the difficulties in aligning the genetic and cytological maps with the genome sequence. The identification of sequence polymorphisms in the Drosophila genome will make it possible to map mutations directly to the genome sequence with high accuracy and resolution. Here we report the identification of 7,223 single-nucleotide… CONTINUE READING
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