Genetic mapping of xthA, the structural gene for exonuclease III in Escherichia coli K-12.

@article{White1976GeneticMO,
  title={Genetic mapping of xthA, the structural gene for exonuclease III in Escherichia coli K-12.},
  author={Bradley J. White and S J Hochhauser and Nitza M. Cintr{\'o}n and Bernard Weiss},
  journal={Journal of bacteriology},
  year={1976},
  volume={126 3},
  pages={1082-8}
}
The genes xthA, pncA, and pabB were ordered relative to others by two- and three-factor transductional crosses with bacteriophage P1. The genes studied span 2 min (2%) of the genetic map of Escherichia coli K-12 in the clockwise sequence pheS-pfkB-xthA-pncA-gap-pabB-fadD. Eleven independently derived xth mutations were examined; all were known to affect exonuclease III and its associated endonuclease II activity, and all were mapped in the xthA region. pncA mutations were found to confer… CONTINUE READING

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