Genetic mapping of adrenergic receptor genes in humans

@article{Hoehe2004GeneticMO,
  title={Genetic mapping of adrenergic receptor genes in humans},
  author={M. R. Hoehe and B. Otterud and W T Hsieh and M M Martinez and D. Stauffer and John J. Holik and Wade H. Berrettini and William Byerley and Elliot S. Gershon and J. M. Lalouel and M. Leppert},
  journal={Journal of Molecular Medicine},
  year={2004},
  volume={73},
  pages={299-306}
}
We have genetically mapped the genes encoding four human adrenergic receptors (ARs) of subtypes α1C, α2A, α2B, and β1, which are prototypic G protein coupled receptors that mediate the physiological effects of neurotransmitters, hormones, and drugs. We placed these genes onto the Cooperative Human Linkage Center (CHLC) and Genethon framework maps, within confidence intervals with greater than 1000∶1 odds. With multipoint analysis the α1C gene (locus ADRA1C) mapped to the interval between NEFL… 
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