Genetic manipulation of blood group carbohydrates alters development and pathfinding of primary sensory axons of the olfactory systems.

@article{John2006GeneticMO,
  title={Genetic manipulation of blood group carbohydrates alters development and pathfinding of primary sensory axons of the olfactory systems.},
  author={James A St John and Christina Claxton and M W Robinson and Fumiichiro Yamamoto and Steven E. Domino and B Key},
  journal={Developmental biology},
  year={2006},
  volume={298 2},
  pages={470-84}
}
Primary sensory neurons in the vertebrate olfactory systems are characterised by the differential expression of distinct cell surface carbohydrates. We show here that the histo-blood group H carbohydrate is expressed by primary sensory neurons in both the main and accessory olfactory systems while the blood group A carbohydrate is expressed by a subset of vomeronasal neurons in the developing accessory olfactory system. We have used both loss-of-function and gain-of-function approaches to… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…