Genetic live vaccines mimic the antigenicity but not pathogenicity of live viruses.

Abstract

The development of an effective HIV vaccine is both a pressing and a formidable problem. The most encouraging results to date have been achieved using live-attenuated immunodeficiency viruses. However, the frequency of pathogenic breakthroughs has been a deterrent to their development. We suggest that expression libraries generated from viral DNA can… (More)

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Cite this paper

@article{Sykes1999GeneticLV, title={Genetic live vaccines mimic the antigenicity but not pathogenicity of live viruses.}, author={Kathryn F Sykes and S A Johnston}, journal={DNA and cell biology}, year={1999}, volume={18 7}, pages={521-31} }