Genetic linkage mapping of the dehydroepiandrosterone sulfotransferase (STD) gene on the chromosome 19q13.3 region.

@article{Durocher1995GeneticLM,
  title={Genetic linkage mapping of the dehydroepiandrosterone sulfotransferase (STD) gene on the chromosome 19q13.3 region.},
  author={Francine Durocher and Jean Morissette and Isabelle Dufort and J. Simard and Van Luu-The},
  journal={Genomics},
  year={1995},
  volume={29 3},
  pages={
          781-3
        }
}
In the human liver and adrenal, there is a single hydroxysteroid sulfotransferase, which catalyzes the transformation of dehydroepiandrosterone to dehydroepiandrosterone sulfate, the most abundantly circulating steroid in humans, and also catalyzes the sulfation of a series of other 3 beta-hydroxysteroids as well as cholesterol. Dehydroepiandrosterone sulfate serves as precursor for the formation of active androgens and estrogens in several peripheral tissues, indicating that hydroxysteroid… CONTINUE READING