Genetic linkage analysis of complex genetic traits by using affected sibling pairs.

@article{Hauser1998GeneticLA,
  title={Genetic linkage analysis of complex genetic traits by using affected sibling pairs.},
  author={Elizabeth R. Hauser and Michael Boehnke},
  journal={Biometrics},
  year={1998},
  volume={54 4},
  pages={1238-46}
}
We provide an introduction to genetic linkage analysis. We discuss methods for the genetic analysis of common, complex disease such as diabetes, heart disease or hypertension. We describe the analysis of affected sibling pairs and discuss some of the challenges in applying these methods. 

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