Genetic landscape of the people of India: a canvas for disease gene exploration

@article{Mukerji2008GeneticLO,
  title={Genetic landscape of the people of India: a canvas for disease gene exploration},
  author={Mitali Mukerji and Shantanu Sengupta and Abhay Sharma and Debasis Dash and Saman Habib and Srikanta Kumar Rath and Devendra Parmar and Jagmohan Singh and Partha Majumder and Ganga Nath Jha and Komal Virdi and Vadlamudi Raghavendra Rao and Shrawan Kumar Mishra and Dwaipayan Bharadwaj and Qadar M A Pasha and Sridhar Sivasubbu and Rajesh Pandey and Aradhita Baral and Prashant Kumar Singh and Amitabh Sharma and Jitender Kumar and Tsering Stobdan and Susanta Roychoudhury and Krishanu Dasgupta and Charles J. Spurgeon and Marshita Mohd Idris and Ashok Kumar Singh and Amit Kumar Mitra and Vinay Khanna and Alok Dhawan and Mohini Anand and Ravi Shankar and Ram Suresh Bharti and Arvind P. Singh and Anwar Jamal Khan and Victor G. Rajamanickam and Eugene Wilson and Neelam Makhija and Abdur Rahim and Sangeeta Sharma and Rupali Chopra and Pooja Pandey Rana and M. Chidambaram and Arindam Maitra and Ruchi Chawla and Suruchika Soni and Preeti Khurana and Mohamed Khan and Sushanta Kumar Das Sutar and Amit Tuteja and Kathiresan Narayansamy and Shalini Mani Tripathi and Nikita Thakur and Balaram Ghosh and Ritushree Kukreti and Taruna Madan and Samir K. Brahmachari and Anubha Mahajan and Sreenivas Chavali and Rubina Tabassum and Sandeep Grover and Meenal Gupta and Jyotsna Batra and Amrendra Kumar and Pankaj Kumar Jha and Abdoulazim Nejatizadeh and Mudit Vaid and Swapan K Das and Shilpy Sharma and Mamta Sharma and Rajshekhar Chatterjee and Jinny A. Paul and Pragya Srivastava and Charu Rajput and Uma Mittal and Mridula Singh and Manoj Hariharan and Sumantra Das and Mainak Sengupta and Gourish Monadal and Shiladitya Sengupta and Dipanjana Dutta De and Ishani Deb and Arunava Banerjee and Rajdeep Chowdhury and Debalina Banerjee and Deepak Kumar and Sumit Ranjan Das and Sumera Parveen and Dipayan Dasgupta and Siddharth Singh Bisht and Ikhlak Ahmed and Sangeeta Khanna and Rashmi Rajput and Biswaroop Ghosh and Naveen Kumar and Amit Chaurasia and James Kappukalayil Abraham and Amit Sinha and Yasha Bhasin and Amit KJ Mandal and Arijit Mukhopadhyay},
  journal={Journal of Genetics},
  year={2008},
  volume={87},
  pages={3-20}
}
Analyses of frequency profiles of markers on disease or drug-response related genes in diverse populations are important for the dissection of common diseases. We report the results of analyses of data on 405 SNPs from 75 such genes and a 5.2 Mb chromosome, 22 genomic region in 1871 individuals from diverse 55 endogamous Indian populations. These include 32 large (> 10 million individuals) and 23 isolated populations, representing a large fraction of the people of India. We observe high levels… CONTINUE READING