Genetic landscape of the people of India: a canvas for disease gene exploration
@article{Brahmachari2008GeneticLO, title={Genetic landscape of the people of India: a canvas for disease gene exploration}, author={S. Brahmachari and P. Majumder and M. Mukerji and S. Habib and Debasis Dash and K. Ray and S. Bahl and L. Singh and A. Sharma and S. Roychoudhury and G. Chandak and K. Thangaraj and D. Parmar and S. Sengupta and D. Bharadwaj and S. Rath and Jagmohan Singh and G. N. Jha and K. Virdi and V. Rao and Swapnil Sinha and Ashutosh Kumar Singh and A. K. Mitra and S. Mishra and Q. Pasha and Sridhar Sivasubbu and R. Pandey and Aradhita Baral and P. K. Singh and J. Kumar and T. Stobdan and Yasha Bhasin and C. Chauhan and Ashiq Hussain and Elyanambi Sundaramoorthy and S. Singh and A. Bandyopadhyay and Krishanu Dasgupta and A. K. Reddy and C. Spurgeon and M. M. Idris and V. Khanna and Alok Dhawan and M. Anand and R. Shankar and R. S. Bharti and M. Singh and A. P. Singh and A. J. Khan and P. P. Shah and A. B. Pant and R. Kaur and K. Bisht and A. Kumar and V. Rajamanickam and E. Wilson and Antony Thangadurai and P. Jha and M. Maulik and N. Makhija and A. Rahim and Sangeeta Sharma and R. Chopra and P. Rana and M. Chidambaram and A. Maitra and R. Chawla and Suruchika Soni and Preeti Khurana and M. N. Khan and S. D. Sutar and Amit Tuteja and K. Narayansamy and R. Shukla and S. Prakash and S. Mahurkar and K. R. Mani and J. Hemavathi and Seema Bhaskar and P. Khanna and G. Ramalakshmi and S. Tripathi and Nikita Thakur and B. Ghosh and R. Kukreti and T. Madan and R. Verma and G. Sudheer and A. Mahajan and S. Chavali and R. Tabassum and Sandeep Grover and Meenal Gupta and J. Batra and Abdoulazim Nejatizadeh and M. Vaid and S. Das and S. Sharma and Mamta Sharma and R. Chatterjee and Jinny A. Paul and Pragya Srivastava and C. Rajput and U. Mittal and M. Hariharan and S. K. Das and K. Chaudhuri and M. Sengupta and M. Acharya and Ashima Bhattacharyya and Atreyee Saha and A. Biswas and M. Chaki and A. Gupta and S. Mukherjee and S. Mookherjee and I. Chattopadhyay and T. Banerjee and M. Chakravorty and C. Misra and Gourish Monadal and Shiladitya Sengupta and Dipanjana Dutta De and Swati Bajaj and Ishani Deb and Arunava Banerjee and R. Chowdhury and D. Banerjee and D. Kumar and S. R. Das and Shrish Tiwari and A. Bharadwaj and I. Ahmed and Sumera Parveen and N. Singh and D. Dasgupta and S. Bisht and S. Khanna and Rashmi Rajput and N. Kumar and Amit Chaurasia and J. Abraham and A. Sinha and V. Scaria and Tavpritesh Sethi and Amit Kj Mandal and A. Mukhopadhyay}, journal={Journal of Genetics}, year={2008}, volume={87}, pages={3-20} }
Analyses of frequency profiles of markers on disease or drug-response related genes in diverse populations are important for the dissection of common diseases. We report the results of analyses of data on 405 SNPs from 75 such genes and a 5.2 Mb chromosome, 22 genomic region in 1871 individuals from diverse 55 endogamous Indian populations. These include 32 large (> 10 million individuals) and 23 isolated populations, representing a large fraction of the people of India. We observe high levels… CONTINUE READING
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References
SHOWING 1-10 OF 59 REFERENCES
Low Levels of Genetic Divergence across Geographically and Linguistically Diverse Populations from India
- Biology, Medicine
- PLoS genetics
- 2006
- 100
- PDF
Positional Cloning of Disease Genes: Advantages of Genetic Isolates
- Biology, Medicine
- Human Heredity
- 1999
- 118
Interrogating a high-density SNP map for signatures of natural selection.
- Biology, Medicine
- Genome research
- 2002
- 844
- PDF
Genetic variation among world populations: inferences from 100 Alu insertion polymorphisms.
- Biology, Medicine
- Genome research
- 2003
- 216
- PDF
Genetic structure of Indian populations based on fifteen autosomal microsatellite loci
- Biology, Medicine
- BMC Genetics
- 2005
- 39
- PDF
Patterns of human genetic diversity: implications for human evolutionary history and disease.
- Biology, Medicine
- Annual review of genomics and human genetics
- 2003
- 366
Ethnic India: a genomic view, with special reference to peopling and structure.
- Biology, Medicine
- Genome research
- 2003
- 336
- PDF
Linkage Disequilibrium: Ancient History Drives the New Genetics
- Biology, Medicine
- Human Heredity
- 2005
- 55
- PDF