Genetic landmarks for defects in mouse neural tube closure.

  title={Genetic landmarks for defects in mouse neural tube closure.},
  author={Muriel J. Harris and Diana M. Juriloff},
  volume={56 3},
Many mutations cause neural tube closure defects (NTDs, exencephaly or spina bifida) in mice and the gene loci are widely distributed in the mouse genome. This compilation summarizes the map position of 40 mouse NTD mutations and the corresponding human linkage homology of each. It includes the nature of the gene product where known, and whether the NTD is part of a syndrome involving other developmental systems. Also listed are the several mouse strains known to have genetic susceptibility to… CONTINUE READING

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