Genetic interactions of the Aspergillus nidulans atmAATM homolog with different components of the DNA damage response pathway.

Abstract

Ataxia telangiectasia mutated (ATM) is a phosphatidyl-3-kinase-related protein kinase that functions as a central regulator of the DNA damage response in eukaryotic cells. In humans, mutations in ATM cause the devastating neurodegenerative disease ataxia telangiectasia. Previously, we characterized the homolog of ATM (AtmA) in the filamentous fungus… (More)
DOI: 10.1534/genetics.107.080879

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