Genetic instability of the global regulator agr explains the phenotype of the xpr mutation in Staphylococcus aureus KSI9051.

@article{McNamara1998GeneticIO,
  title={Genetic instability of the global regulator agr explains the phenotype of the xpr mutation in Staphylococcus aureus KSI9051.},
  author={Peter J. McNamara and John J. Iandolo},
  journal={Journal of bacteriology},
  year={1998},
  volume={180 10},
  pages={2609-15}
}
Staphylococcus aureus KSI9051 has a complex mutation that was associated with the aberrant expression of cell surface and extracellular proteins (M. S. Smeltzer, M. E. Hart, and J. J. Iandolo, J. Bacteriol. 61:919-925, 1993). This mutation was named xpr, although no specific gene was identified. Here this mutation is referred to as Delta1058::Tn551. In this study, we show that in strain KSI9051, the Delta1058::Tn551 mutation occurred coincidentally with a frameshift in agrC that is expected to… CONTINUE READING

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