Genetic insights into the neurodevelopmental origins of schizophrenia

  title={Genetic insights into the neurodevelopmental origins of schizophrenia},
  author={Rebecca Birnbaum and Daniel R. Weinberger},
  journal={Nature Reviews Neuroscience},
Schizophrenia is a severe neuropsychiatric disorder with a longstanding history of neurobiological investigation. Although the underlying causal mechanisms remain unknown, early neurodevelopmental events have been implicated in pathogenesis, initially by epidemiological and circumstantial data but more recently by brain-specific molecular and genetic findings. Notably, genomic research has recently uncovered discrete risk variants and risk loci associated with schizophrenia, with the potential… 
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