Genetic influences on the outcome of anti-vascular endothelial growth factor treatment in neovascular age-related macular degeneration.

@article{Abedi2013GeneticIO,
  title={Genetic influences on the outcome of anti-vascular endothelial growth factor treatment in neovascular age-related macular degeneration.},
  author={Farshad Abedi and Sanjeewa S Wickremasinghe and Andrea Jane Richardson and A. H. M. Forhadul Islam and Robyn H. Guymer and Paul N Baird},
  journal={Ophthalmology},
  year={2013},
  volume={120 8},
  pages={1641-8}
}
PURPOSE To determine the association of genetic variants in known age-related macular degeneration (AMD) risk-associated genes with outcome of anti-vascular endothelial growth factor (VEGF) treatment in neovascular AMD. DESIGN Prospective cohort study. PARTICIPANTS We enrolled 224 consecutive patients with neovascular AMD at the Royal Victorian Eye and Ear Hospital, Australia. METHODS Patients were treated with 3 initial monthly ranibizumab or bevacizumab injections followed by 9 months… CONTINUE READING
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