Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction

  title={Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction},
  author={Mary Jeanne Kreek and David A. Nielsen and Eduardo R Butelman and K. Steven LaForge},
  journal={Nature Neuroscience},
Genetic variation may partially underlie complex personality and physiological traits—such as impulsivity, risk taking and stress responsivity—as well as a substantial proportion of vulnerability to addictive diseases. Furthermore, personality and physiological traits themselves may differentially affect the various stages of addiction, defined chronologically as initiation of drug use, regular drug use, addiction/dependence and potentially relapse. Here we focus on recent approaches to the… 

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  • Psychology, Medicine
    Molecular psychiatry
  • 1996
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