Genetic influences on hippocampal volume differ as a function of testosterone level in middle-aged men

@article{Panizzon2012GeneticIO,
  title={Genetic influences on hippocampal volume differ as a function of testosterone level in middle-aged men},
  author={Matthew S. Panizzon and Richard L. Hauger and Lindon J. Eaves and Chi-Hua Chen and Anders M. Dale and Lisa T. Eyler and Bruce Fischl and Christine Fennema-Notestine and Carol E. Franz and Michael D. Grant and Kristen C. Jacobson and Amy J. Jak and Michael J. Lyons and Sally P. Mendoza and Michael C. Neale and Elizabeth Prom-Wormley and Larry J. Seidman and Ming T. Tsuang and Hong Xian and William S. Kremen},
  journal={NeuroImage},
  year={2012},
  volume={59},
  pages={1123-1131}
}
The hippocampus expresses a large number of androgen receptors; therefore, in men it is potentially vulnerable to the gradual age-related decline of testosterone levels. In the present study we sought to elucidate the nature of the relationship between testosterone and hippocampal volume in a sample of middle-aged male twins (average age 55.8 years). We found no evidence for a correlation between testosterone level and hippocampal volume, as well as no indication of shared genetic influences… CONTINUE READING
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1123–1131 II. Rationale and applications with systematics of cerebral

  • M. S. Panizzon
  • connectivity. Neuroimage
  • 2012

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