Genetic influences on brain structure

@article{Thompson2001GeneticIO,
  title={Genetic influences on brain structure},
  author={P. Thompson and Tyrone D. Cannon and K. Narr and T. V. Erp and V. Poutanen and M. Huttunen and J. L{\"o}nnqvist and C. Standertskj{\"o}ld-Nordenstam and J. Kaprio and Mohammad Khaledy and R. Dail and C. Zoumalan and A. Toga},
  journal={Nature Neuroscience},
  year={2001},
  volume={4},
  pages={1253-1258}
}
  • P. Thompson, Tyrone D. Cannon, +10 authors A. Toga
  • Published 2001
  • Psychology, Medicine
  • Nature Neuroscience
  • Here we report on detailed three-dimensional maps revealing how brain structure is influenced by individual genetic differences. A genetic continuum was detected in which brain structure was increasingly similar in subjects with increasing genetic affinity. Genetic factors significantly influenced cortical structure in Broca's and Wernicke's language areas, as well as frontal brain regions (r2MZ > 0.8, p < 0.05). Preliminary correlations were performed suggesting that frontal gray matter… CONTINUE READING
    910 Citations

    Figures, Tables, and Topics from this paper.

    Explore Further: Topics Discussed in This Paper

    Paper Mentions

    Mapping genetic influences on human brain structure
    • 92
    • PDF
    Genetics of brain structure and intelligence.
    • 278
    • PDF
    Genetic influences on human brain morphology
    • 7
    The contribution of genes to cortical thickness and volume
    • 79
    • PDF
    A genetic analysis of cortical thickness in 372 twins
    • A. Joshi, N. Lepore, +7 authors P. Thompson
    • Biology, Computer Science
    • 2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro
    • 2010
    • 1
    • PDF
    Genetic influences on human brain structure: A review of brain imaging studies in twins
    • 401
    • Highly Influenced
    • PDF
    Heritability of structural brain traits an endophenotype approach to deconstruct schizophrenia.
    • 32
    • Highly Influenced
    Genetics and Brain Morphology
    • 30

    References

    SHOWING 1-10 OF 64 REFERENCES
    Genetic variability of human brain size and cortical gyral patterns.
    • 329
    • PDF
    A Twin MRI Study of Size Variations in the Human Brain
    • 188
    The inheritance of neuropsychological dysfunction in twins discordant for schizophrenia.
    • 361
    Genetics and child psychiatry: I Advances in quantitative and molecular genetics.
    • 163