Genetic influences determining progenitor cell mobilization and leukocytosis induced by granulocyte colony-stimulating factor.

@article{Roberts1997GeneticID,
  title={Genetic influences determining progenitor cell mobilization and leukocytosis induced by granulocyte colony-stimulating factor.},
  author={Andrew W Roberts and Simon Foote and Warren S. Alexander and Clare H Scott and Lorraine Robb and Donald Metcalf},
  journal={Blood},
  year={1997},
  volume={89 8},
  pages={2736-44}
}
The mechanisms involved in the mobilization of progenitor cells into the blood by granulocyte colony-stimulating factor (G-CSF) and other cytokines are poorly understood. To identify important influences on this complex process, in vivo murine models were used. Granulocyte-macrophage colony-stimulating factor (GM-CSF) transgenic, Max41 transgenic, W/Wv, Mpl-null, GM-CSF receptor (beta chain)-null mice, wild-type littermate controls, and six inbred strains of mice were injected with 200 microg… CONTINUE READING
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and defective megakaryocytopoiesis in mice lacking the thrombopoietin receptor cmpl

  • R Basser, CG Begley, +16 authors C Begley
  • Blood
  • 1996

Binding of 125 Ilabeled granulocytetopoiesis in max 41 transgenic mice with sustained excess granulopoiesis

  • NA Nicola, D Metcalf
  • Blood
  • 1995

The regulation of hema- teers

  • D Metcalf, AW Roberts, TA Willson
  • Blood 86:4437,
  • 1995

Dexterto granulocytic switch during hematopoiesis in a transgenic mouse strain

  • G Molineux, A Migdalska, M Szmitkowski, K Zsebo
  • Immunity
  • 1994

mobilized by four different protocols and those of steady-phase PB and bone marrow CD34 cells

  • PA Chervenick, DR Boggs, JC Marsh, GE Cartwright, Win
  • Blood 84:2930,
  • 1994

Granulocyte-macrophage colony stimulating factor tlety

  • MA Socinski, SA Cannistra, A Elias, KH Antman, L Schnipper, JD Griffin
  • Blood 82:3515,
  • 1993

Regulated proliferation ofexpands the circulating haemopoietic progenitor cell compartment in man

  • J Cashman, AC Eaves, CJ Eaves
  • Blood
  • 1993

Deficiencies in progenitor cells of multiple hematopoietic lineages combination with granulocyte colony-stimulating factor

  • WS Alexander, AW Roberts, NA Nicola, R Li, D Metcalf
  • Blood 78:961,
  • 1991

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