Genetic influence on peripheral blood T lymphocyte levels

Abstract

T lymphocytes are a major component of the adaptive immune system. CD4 positive T cell subpopulations regulate B cell and macrophage effector function while CD8 positive T cells are largely responsible for anti-viral cytotoxic activity. The degree of natural variation in the levels and ratios of the various T cell subpopulations is a possible risk factor… (More)
DOI: 10.1038/sj.gene.6363702

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