Genetic influence on human lifespan and longevity

  title={Genetic influence on human lifespan and longevity},
  author={Jacob V B Hjelmborg and Ivan A. Iachine and Axel E Skytthe and James W. Vaupel and Matt McGue and Markku Koskenvuo and Jaakko M Kaprio and Nancy L Pedersen and Kaare Christensen},
  journal={Human Genetics},
There is an intense search for longevity genes in both animal models and humans. Human family studies have indicated that a modest amount of the overall variation in adult lifespan (approximately 20–30%) is accounted for by genetic factors. But it is not known if genetic factors become increasingly important for survival at the oldest ages. We study the genetic influence on human lifespan and how it varies with age using the almost extinct cohorts of Danish, Finnish and Swedish twins born… CONTINUE READING
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