Genetic imbalances in endometrial hyperplasia and endometrioid carcinoma detected by comparative genomic hybridization.


OBJECTIVE To evaluate the sequential genomic copy alterations related to the development of precursor lesions and endometrioid-type endometrial carcinomas, and its association with cellular atypia. STUDY DESIGN Paraffin-embedded tissue specimens from 32 cases of endometrial hyperplasia, 15 of endometrial carcinoma, and 20 of normal endometrial tissue were… (More)


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