Genetic imbalances in endometrial hyperplasia and endometrioid carcinoma detected by comparative genomic hybridization.

Abstract

OBJECTIVE To evaluate the sequential genomic copy alterations related to the development of precursor lesions and endometrioid-type endometrial carcinomas, and its association with cellular atypia. STUDY DESIGN Paraffin-embedded tissue specimens from 32 cases of endometrial hyperplasia, 15 of endometrial carcinoma, and 20 of normal endometrial tissue were… (More)

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