Genetic identification and characterization of a novel virus related to human hepatitis E virus from chickens with hepatitis-splenomegaly syndrome in the United States.
@article{Haqshenas2001GeneticIA, title={Genetic identification and characterization of a novel virus related to human hepatitis E virus from chickens with hepatitis-splenomegaly syndrome in the United States.}, author={G. Haqshenas and H. Shivaprasad and P. Woolcock and D. Read and X. Meng}, journal={The Journal of general virology}, year={2001}, volume={82 Pt 10}, pages={ 2449-62 } }
Hepatitis-splenomegaly (HS) syndrome is an emerging disease in chickens in North America; the cause of this disease is unknown. In this study, the genetic identification and characterization of a novel virus related to human hepatitis E virus (HEV) isolated from bile samples of chickens with HS syndrome is reported. Based upon the similar genomic organization and significant sequence identity of this virus with HEV, the virus has been tentatively named avian HEV in order to distinguish it from… CONTINUE READING
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References
SHOWING 1-10 OF 76 REFERENCES
An Indian strain of hepatitis E virus (HEV): cloning, sequence, and expression of structural region and antibody responses in sera from individuals from an area of high-level HEV endemicity.
- Biology, Medicine
- Journal of clinical microbiology
- 1995
- 93
- PDF
The sequence and phylogenetic analysis of a novel hepatitis E virus isolated from a patient with acute hepatitis reported in the United States.
- Biology, Medicine
- The Journal of general virology
- 1998
- 351
- Highly Influential
Molecular cloning and sequencing of the Mexico isolate of hepatitis E virus (HEV).
- Biology, Medicine
- Virology
- 1992
- 334
Genetic and Experimental Evidence for Cross-Species Infection by Swine Hepatitis E Virus
- Biology, Medicine
- Journal of Virology
- 1998
- 545
- PDF
Identity of a Novel Swine Hepatitis E Virus in Taiwan Forming a Monophyletic Group with Taiwan Isolates of Human Hepatitis E Virus
- Biology, Medicine
- Journal of Clinical Microbiology
- 1999
- 261
- PDF
A divergent genotype of hepatitis E virus in Chinese patients with acute hepatitis.
- Biology, Medicine
- The Journal of general virology
- 1999
- 221
- Highly Influential
A novel virus in swine is closely related to the human hepatitis E virus.
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 1997
- 1,026
- Highly Influential
- PDF
Characterization of a prototype strain of hepatitis E virus.
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 1992
- 266
- PDF
A hepatitis E virus variant from the United States: molecular characterization and transmission in cynomolgus macaques.
- Biology, Medicine
- The Journal of general virology
- 1999
- 204
- Highly Influential
Hepatitis E virus (HEV): Molecular cloning and sequencing of the full-length viral genome
- Biology, Medicine
- Virology
- 1991
- 930