Genetic homology and crossing over in the X and Y chromosomes of mammals

@article{Burgoyne1982GeneticHA,
  title={Genetic homology and crossing over in the X and Y chromosomes of mammals},
  author={Paul S. Burgoyne},
  journal={Human Genetics},
  year={1982},
  volume={61},
  pages={85-90}
}
The “X-Y crossover model” described in this paper postulates that (1) the pairing observed between the X and the Y chromosome at zygotene is a consequence of genetic homology, (2) there is a single obligatory crossover between the X and Y pairing segments, and (3) the segment of the X which pairs with the Y is protected from subsequent X inactivation. Genes distal to the proposed crossover (“pseudoautosomal genes”) will appear to be autosomally inherited because they will be transmitted to both… CONTINUE READING
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