Genetic heterozygosity in a natural population of Mus musculus assessed using two-dimensional electrophoresis

@article{Racine1980GeneticHI,
  title={Genetic heterozygosity in a natural population of Mus musculus assessed using two-dimensional electrophoresis},
  author={Robert R. Racine and Charles H. Langley},
  journal={Nature},
  year={1980},
  volume={283},
  pages={855-857}
}
Since the introduction of gel electrophoresis to population genetics, estimates of genie heterozygosity at allozyme loci have been made for many organisms1. However, attempts to extend the range of proteins surveyed2–4 have been hampered by concern that there may have been bias in the loci sampled: nearly all proteins for which population data are available are soluble in low-salt extracts and most are enzymes belonging to particular groups such as the nonspecific esterases and phosphatases… CONTINUE READING
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