Genetic heterogeneity and phylogeny of Trichuris spp. from captive non-human primates based on ribosomal DNA sequence data.

Abstract

Nematodes of the genus Trichuris, known as whipworms, are recognized to infect numerous mammalian species including humans and non-human primates. Several Trichuris spp. have been described and species designation/identification is traditionally based on host-affiliation, although cross-infection and hybridization events may complicate species boundaries. The main aims of the present study were to genetically characterize adult Trichuris specimens from captive Japanese macaques (Macaca fuscata) and grivets (Chlorocebus aethiops), using the ribosomal DNA (ITS) as molecular marker and to investigate the phylogeny and the extent of genetic variation also by comparison with data on isolates from other humans, non-human primates and other hosts. The phylogenetic analysis of Trichuris sequences from M. fuscata and C. aethiops provided evidences of distinct clades and subclades thus advocating the existence of additional separated taxa. Neighbor Joining and Bayesian trees suggest that specimens from M. fuscata may be distinct from, but related to Trichuris trichiura, while a close relationship is suggested between the subclade formed by the specimens from C. aethiops and the subclade formed by T. suis. The tendency to associate Trichuris sp. to host species can lead to misleading taxonomic interpretations (i.e. whipworms found in primates are identified as T. trichiura). The results here obtained confirm previous evidences suggesting the existence of Trichuris spp. other than T. trichiura infecting non-human living primates.

DOI: 10.1016/j.meegid.2015.06.009

3 Figures and Tables

050020162017
Citations per Year

269 Citations

Semantic Scholar estimates that this publication has 269 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Cavallero2015GeneticHA, title={Genetic heterogeneity and phylogeny of Trichuris spp. from captive non-human primates based on ribosomal DNA sequence data.}, author={Serena Cavallero and Claudio De Liberato and Klaus Friedrich and David Di Cave and Valentina Masella and Stefano D'Am{\'e}lio and Federica Berrilli}, journal={Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases}, year={2015}, volume={34}, pages={450-6} }