Genetic growth potential interacts with nutrition on the ability of mice to cope with Heligmosomoides bakeri infection.

@article{Coltherd2009GeneticGP,
  title={Genetic growth potential interacts with nutrition on the ability of mice to cope with Heligmosomoides bakeri infection.},
  author={Jennifer C Coltherd and Lutz B{\"u}nger and Ilias Kyriazakis and Jos G. M. Houdijk},
  journal={Parasitology},
  year={2009},
  volume={136 9},
  pages={1043-55}
}
Artificial selection for improved productivity may reduce an animal's ability to cope with pathogens. Here, we used Roslin mice, uniquely divergently selected for high (ROH) and low (ROL) body weight, to assess interactive effects of differing growth potential and protein nutrition on host resilience and resistance. In a 2 x 2 x 6 factorial design, ROH and ROL mice were either sham-infected or infected with 250 L(3)Heligmosomoides bakeri and fed diets with 30, 80, 130, 180, 230 and 280 g crude… CONTINUE READING

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