Genetic factors in susceptibility to death: a comparative analysis of bivariate survival models.

@article{Yashin1999GeneticFI,
  title={Genetic factors in susceptibility to death: a comparative analysis of bivariate survival models.},
  author={Anatoliy I. Yashin and Alexander Z. Begun and Ivan A. Iachine},
  journal={Journal of epidemiology and biostatistics},
  year={1999},
  volume={4 1},
  pages={53-60}
}
BACKGROUND Molecular epidemiological studies of aging and longevity are focused on evaluating the effects of single genes on susceptibility to disease and death. The effects of all genetic factors on susceptibility can be evaluated from the analysis of survival data on related individuals. METHOD The analyses of survival data on Danish monozygotic (MZ) and dizygotic (DZ) twins are performed using gamma, inverse Gaussian and three-parameter correlated frailty models. The semiparametric… CONTINUE READING