Genetic factors as a cause of miscarriage.

  title={Genetic factors as a cause of miscarriage.},
  author={Nobuhiro Suzumori and Mayumi Sugiura-Ogasawara},
  journal={Current medicinal chemistry},
  volume={17 29},
Aneuploidy in the conceptus or fetus, occurs in 5-10% of all pregnancies and is a common reproductive problem in humans. Most aneuploid conceptuses die in utero, resulting in early pregnancy loss. Causes of recurrent miscarriage may include abnormal chromosomes in either partner, particularly translocations, antiphospholipid antibodies and uterine anomalies. Chromosomal aberrations in parents are a major pre-disposing factor and causative of abortion if carried over to the embryo. The… 

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