Genetic evidence of assortative mating in humans

  title={Genetic evidence of assortative mating in humans},
  author={Matthew R. Robinson and Aaron Kleinman and Mariaelisa Graff and Anna A. E. Vinkhuyzen and David J Couper and Michael B. Miller and Wouter J. Peyrot and Abdel Abdellaoui and Brendan P. Zietsch and Ilja Maria Nolte and Jana V. van Vliet-Ostaptchouk and Harold Snieder and Sarah E. Medland and Nicholas G. Martin and Patrik K. E. Magnusson and William G. Iacono and Matt McGue and Kari E. North and Jian Yang and Peter M. Visscher},
  journal={Nature Human Behaviour},
In human populations, assortative mating is almost univer­sally positive, with similarities between partners for quantit­ative phenotypes1–6, common disease risk1,3,7–10, beha­vi­our6,11, social factors12–14 and personality4,5,11. The causes and genetic consequences of assortative mating remain un­re­solved because partner similarity can arise from different mechanisms: phenotypic assortment based on mate choice15,16, partner interaction and convergence in phenotype over time14,17, or social… 
Imprint of assortative mating on the human genome
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Assortative mating (AM) occurs when the correlation for a trait between mates is larger than would be expected by chance. AM can increase the genetic and environmental variation of traits, can
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Increased phenotypic similarity between partners, termed assortative mating (AM), has been observed for many traits. However, it is currently unclear if these observations are due to mate choice for
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Assortative Mating on Ancestry-Variant Traits in Admixed Latin American Populations
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No evidence for genetic assortative mating beyond that due to population stratification
It is argued that, although the reported result is descriptively true, the spousal genetic similarity can be explained by assortment on shared ancestry and thus does not reflect genetic assortative mating as interpreted by Dominigue et al.
Variation in Human Mate Choice: Simultaneously Investigating Heritability, Parental Influence, Sexual Imprinting, and Assortative Mating
The main discernible pattern of mate choice was assortative mating and it was found that partner similarity was due to initial choice rather than convergence and also at least in part to phenotypic matching.
Genomic Assortative Mating in Marriages in the United States
Using genome-wide genotype data from the Framingham Heart study and Health Retirement Survey, genomic assortative mating in human marriages is investigated and SNP-specific correlation “averaged” over all married couples is estimated.
Assortative mating may explain spouses' risk of same disease
The results show that different mechanisms underlie similarities between spouses for health behaviour, social factors, and personality traits, and that assortative mating should not be hastily dismissed as a cause for spouse similarities in disease.
Genetic and socioeconomic study of mate choice in Latinos reveals novel assortment patterns
An integrative analysis of a large cohort of Mexican and Puerto Rican couples using detailed socioeconomic attributes and genotypes found that in ethnically homogeneous Latino communities, partners are significantly more similar in their genomic ancestries than expected by chance.
Testing for non‐random mating: evidence for ancestry‐related assortative mating in the Framingham heart study
It is shown that the single nucleotide polymorphisms loading most heavily on the first principal component show an excess of homozygotes within the spouses, consistent with similar ancestry‐related assortative mating in the previous generation, and decreases the rate of decay of linkage disequilibrium for ancestrally informative markers.
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It is found that spouses are more genetically similar than two individuals chosen at random but this similarity is at most one-third the magnitude of educational similarity.
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Estimates of the genetic contribution to height choice in mates in 13,068 genotyped couples provide new insight into the mechanisms that govern mate choice in humans and warrant the search for the genetic causes of choice of mate height.
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Data on the educational attainments of adult twin pairs and their spouses from the Virginia twin registry are reported which give no indication of a major decline in the intensity of assortative mating.
Resolving the effects of phenotype and social background on mate selection
Power simulations show that it will be feasible to resolve the contributions of phenotype and social background to mate selection for variables such as IQ, education, and attitudes for which the marital correlation is moderately high.