Genetic evidence linking lung cancer and COPD: a new perspective

  title={Genetic evidence linking lung cancer and COPD: a new perspective},
  author={Robert Peter Young and Raewyn Janice Hopkins and Gregory David Gamble and Carol Jean Etzel and Randa El-Zein and James D. Crapo},
  booktitle={The application of clinical genetics},
Epidemiological studies indicate that tobacco smoke exposure accounts for nearly 90% of cases of chronic obstructive pulmonary disease (COPD) and lung cancer. However, genetic factors may explain why 10%-30% of smokers develop these complications. This perspective reviews the evidence suggesting that COPD is closely linked to susceptibility to lung cancer and outlines the potential relevance of this observation. Epidemiological studies show that COPD is the single most important risk factor for… CONTINUE READING


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Lung cancer assessment tool

  • PB Bach
  • Available from: http://www. Accessed…
  • 2011

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