Genetic evidence for direct sensing of phenolic compounds by the VirA protein of Agrobacterium tumefaciens.

@article{Lee1995GeneticEF,
  title={Genetic evidence for direct sensing of phenolic compounds by the VirA protein of Agrobacterium tumefaciens.},
  author={Yin Won Lee and Shouguang Jin and Woong Seop Sim and Eugene W. Nester},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1995},
  volume={92 26},
  pages={12245-9}
}
The virulence (vir) genes of Agrobacterium tumefaciens are induced by low-molecular-weight phenolic compounds and monosaccharides through a two-component regulatory system consisting of the VirA and VirG proteins. However, it is not clear how the phenolic compounds are sensed by the VirA/VirG system. We tested the vir-inducing abilities of 15 different phenolic compounds using four wild-type strains of A. tumefaciens--KU12, C58, A6, and Bo542. We analyzed the relationship between structures of… CONTINUE READING

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