Genetic evidence against intramolecular rejoining of the donor DNA molecule following IS10 transposition.

Abstract

Tn10 and IS10 transpose by a nonreplicative mechanism in which the transposon is excised from the donor molecule and integrated into a target DNA site, leaving behind a break at the original donor site. The fate of this broken donor DNA molecule is not known. We describe here two experiments that address this issue. One experiment demonstrates that a polar… (More)

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@article{Bender1991GeneticEA, title={Genetic evidence against intramolecular rejoining of the donor DNA molecule following IS10 transposition.}, author={Judith Bender and James Kuo and Nancy E Kleckner}, journal={Genetics}, year={1991}, volume={128 4}, pages={687-94} }