Genetic epidemiological approaches to the search for osteoporosis genes.

  title={Genetic epidemiological approaches to the search for osteoporosis genes.},
  author={Thao Nguyen and John Blangero and John A. Eisman},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  volume={15 3},
Important progress has been made in the identification of specific environmental factors and estimation of hereditary components in bone density, quantitative ultrasound (QUS), and bone turnover indices. By contrast, the search for specific genes that regulate bone mass has progressed rather slowly, and the results are more difficult to interpret and reproduce. This article reviews the genetics of osteoporosis and problems plaguing genetic research. It is argued that the search for genes… CONTINUE READING


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