Genetic engineering compared to natural genetic variations.

  title={Genetic engineering compared to natural genetic variations.},
  author={Werner Arber},
  journal={New biotechnology},
  volume={27 5},
By comparing strategies of genetic alterations introduced in genetic engineering with spontaneously occurring genetic variation, we have come to conclude that both processes depend on several distinct and specific molecular mechanisms. These mechanisms can be attributed, with regard to their evolutionary impact, to three different strategies of genetic variation. These are local nucleotide sequence changes, intragenomic rearrangement of DNA segments and the acquisition of a foreign DNA segment… CONTINUE READING
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