[Genetic effects on physical growth items of child twins in Han nationality].

Abstract

OBJECTIVE To analyse the heritabilities of physical growth items of body and its related factors. METHODS An 116 twin pairs of Han nationality, 67 monozygotic (MZ) and 49 like-sex dizygotic (DZ) aged 6 to 12 years, were investigated from June to October in 2004. The measurements included height, weight, sitting height, chest circumference, biacromial breadth and biiliac breadth, and BMI index calculated by the former two measurements. The heritabilities were estimated by using intraclass correlation coefficient method from the adjusted data for age. RESULTS The intraclass correlation coefficient was greater in the MZ twins than in the DZ twins. The estimated heritabilities of height, weight, BMI, sitting height, chest circumference, biacromial breadth and biiliac breadth were 0.89, 0.88, 0.73, 0.87, 0.78, 0.78, 0.73 in boys and 0.87, 0.74, 0.72, 0.86, 0.62, 0.56, 0.59 in girls adjusted for age. Therefore, there were no sex difference for the heritabilities of height, sitting height and BMI, but the male heritabilities of weight, chest circumference, biacromial breadth and biiliac breadth were higher than the female's respectively. CONCLUSION Physical growth items should be mainly determined by the genetic factors. There are sex differences for the heritabilities of weight, chest circumference, biacromial breadth and biiliac breadth, i.e., the girls might be affected more easily by environmental factors than the boys in these items.

Cite this paper

@article{Li2005GeneticEO, title={[Genetic effects on physical growth items of child twins in Han nationality].}, author={Yu-Ling Li and Cheng Ji and Shun-hua Lu and Li-ya Suo and Jin-lan Bai and Xiao-min Yang and Xiao-Yan Wen and Wei Wang}, journal={Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]}, year={2005}, volume={39 5}, pages={345-7} }