Genetic effects for femoral biomechanics, structure, and density in C57BL/6J and C3H/HeJ inbred mouse strains.

@article{Koller2003GeneticEF,
  title={Genetic effects for femoral biomechanics, structure, and density in C57BL/6J and C3H/HeJ inbred mouse strains.},
  author={Daniel L. Koller and Jennifer Schriefer and Qiwei Sun and Kathryn L. Shultz and Leah Rae B Donahue and Clifford J. Rosen and Tatiana Foroud and Wesley G. Beamer and C. H. Turner},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2003},
  volume={18 10},
  pages={1758-65}
}
UNLABELLED Genome-wide QTL analysis for bone density, structure, and biomechanical phenotypes was performed in 999 (B6xC3H)F2 mice. Multivariate phenotypes were also derived to test for pleiotropic QTL effects. Highly significant QTLs were detected with pleiotropic effects on many of these phenotypes, and QTLs with unique effects on specific phenotypes were found as well. INTRODUCTION The inbred C57BL/6J (B6) and C3H/HeJ (C3H) mouse strains were previously shown to segregate quantitative… CONTINUE READING

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