Genetic drift vs. natural selection in a long-term small isolated population: major histocompatibility complex class II variation in the Gulf of California endemic porpoise (Phocoena sinus).

@article{MunguaVega2007GeneticDV,
  title={Genetic drift vs. natural selection in a long-term small isolated population: major histocompatibility complex class II variation in the Gulf of California endemic porpoise (Phocoena sinus).},
  author={Adri{\'a}n Mungu{\'i}a-Vega and Yareli Esquer-Garrigos and Lorenzo Rojas-Bracho and Ricardo V{\'a}zquez-Ju{\'a}rez and Aines Castro-Prieto and Sergio Flores-Ram{\'i}rez},
  journal={Molecular ecology},
  year={2007},
  volume={16 19},
  pages={4051-65}
}
Although many studies confirm long-term small isolated populations (e.g. island endemics) commonly sustain low neutral genetic variation as a result of genetic drift, it is less clear how selection on adaptive or detrimental genes interplay with random forces. We investigated sequence variation at two major histocompatibility complex (Mhc) class II loci on a porpoise endemic to the upper Gulf of California, México (Phocoena sinus, or vaquita). Its unique declining population is estimated around… CONTINUE READING
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