Genetic diversity as a marker for timing infection in HIV-infected patients: evaluation of a 6-month window and comparison with BED.

@article{RagonnetCronin2012GeneticDA,
  title={Genetic diversity as a marker for timing infection in HIV-infected patients: evaluation of a 6-month window and comparison with BED.},
  author={Manon Ragonnet-Cronin and St{\'e}phane Aris-Brosou and Isabelle Joanisse and Harriet W Merks and Dominic Vall{\'e}e and Kyna Caminiti and Michael L Rekart and Mel Krajden and Darrel Cook and J J Kim and Laurie Malloch and Paul A Sandstrom and James Brooks},
  journal={The Journal of infectious diseases},
  year={2012},
  volume={206 5},
  pages={756-64}
}
BACKGROUND It has been reported that the increase in human immunodeficiency virus (HIV) sequence diversity in drug resistance surveillance specimens may be used to classify the duration of HIV infection as <1 or >1 year. We describe a mixed base classifier (MBC) optimized to categorize the duration of subtype B infections as <6 or >6 months on the basis of sequences for drug resistance surveillance specimens and compared MBC findings with those of serologic methods. METHODS The behavior of… CONTINUE READING
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