Genetic diversity and virulence potential of environmental Vibrio cholerae population in a cholera-endemic area.

@article{Faruque2004GeneticDA,
  title={Genetic diversity and virulence potential of environmental Vibrio cholerae population in a cholera-endemic area.},
  author={Shah M Faruque and Nityananda Chowdhury and Muhammad Kamruzzaman and Michelle Dziejman and Md Hasibur Rahman and David A Sack and Gopinath Balakrish Nair and John J Mekalanos},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 7},
  pages={
          2123-8
        }
}
To understand the evolutionary events and possible selection mechanisms involved in the emergence of pathogenic Vibrio cholerae, we analyzed diverse strains of V. cholerae isolated from environmental waters in Bangladesh by direct enrichment in the intestines of adult rabbits and by conventional laboratory culture. Strains isolated by conventional culture were mostly (99.2%) negative for the major virulence gene clusters encoding toxin-coregulated pilus (TCP) and cholera toxin (CT) and were… CONTINUE READING

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