Genetic diversity and evolution of the human leptin locus tetranucleotide repeat

Abstract

To better understand the evolutionary history of the gene region containing the multifunctional adipose tissue hormone leptin, we genotyped 1,957 individuals from 12 world populations for a highly variable tetranucleotide repeat polymorphism located 476 bp 3′ of exon 3 of the leptin gene. Common alleles shared among populations, alleles specific to… (More)
DOI: 10.1007/s00439-002-0715-5

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