Genetic diversities of MT-ND1 and MT-ND2 genes are associated with high-altitude adaptation in yak.

@article{Shi2018GeneticDO,
  title={Genetic diversities of MT-ND1 and MT-ND2 genes are associated with high-altitude adaptation in yak.},
  author={Yu Shi and Yongsong Hu and Jie Wang and Mauricio A. Elzo and Xue Yang and Songjia Lai},
  journal={Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis},
  year={2018},
  volume={29 3},
  pages={
          485-494
        }
}
Tibetan yak (Bos grunniens) inhabiting the Qinghai-Tibet Plateau (QTP) where the average altitude is 4000 m, is specially adapted to live at these altitudes. Conversely, cattle (B. taurus) has been found to suffer from high-altitude hypertension or heart failure when exposed to these high altitudes. Two mitochondrial genes, MT-ND1 and MT-ND2, encode two subunits of NADH dehydrogenase play an essential role in the electron transport chain of oxidative phosphorylation (OXPHOS). We sequenced these… CONTINUE READING
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