Genetic dissection of sexual orientation: behavioral, cellular, and molecular approaches in Drosophila melanogaster

  title={Genetic dissection of sexual orientation: behavioral, cellular, and molecular approaches in Drosophila melanogaster},
  author={D. Yamamoto and H. Ito and K. Fujitani},
  journal={Neuroscience Research},
  • D. Yamamoto, H. Ito, K. Fujitani
  • Published 1996
  • Biology, Medicine
  • Neuroscience Research
  • Insertional mutagenesis using P-element vectors yielded several independent mutations that cause male homosexuality in Drosophila melanogaster. Subsequent analyses revealed that all of these insertions were located at the same chromosomal division, 91B, where one of the inversion breakpoints responsible for the bisexual phenotype of the fruitless (fru) mutant has been mapped. In addition to the altered sexual orientation, the fru mutants displayed a range of defects in the formation of a male… CONTINUE READING
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