Genetic dissection of neuronal pathways controlling energy homeostasis.

  title={Genetic dissection of neuronal pathways controlling energy homeostasis.},
  author={Nina Balthasar},
  volume={14 Suppl 5},
Recent research has identified a number of genes playing critical roles in the central regulation of energy homeostasis. Subsequently, models of the neurocircuitry regulating energy balance have been suggested, although their physiological relevance remains mostly untested. Using the Cre/loxP system, we can now genetically dissect these neurocircuits and establish the specific roles of these genes in small neuronal subpopulations. Here we focus on two receptors shown to be critical in the… CONTINUE READING