Genetic dissection of functional contributions of specific potassium channel subunits in habituation of an escape circuit in Drosophila.

@article{Engel1998GeneticDO,
  title={Genetic dissection of functional contributions of specific potassium channel subunits in habituation of an escape circuit in Drosophila.},
  author={Jeff E. Engel and Chun Fu Wu},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1998},
  volume={18 6},
  pages={2254-67}
}
Potassium channels have been implicated in central roles in activity-dependent neural plasticity. The giant fiber escape pathway of Drosophila has been established as a model for analyzing habituation and its modification by memory mutations in an identified circuit. Several genes in Drosophila encoding K+ channel subunits have been characterized, permitting examination of the contributions of specific channel subunits to simple conditioning in an identified circuit that is amenable to genetic… CONTINUE READING
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