Genetic differences in HLA-DQA1* and DQB1* allelic distributions between celiac and control children in Santiago, Chile.

@article{PrezBravo1999GeneticDI,
  title={Genetic differences in HLA-DQA1* and DQB1* allelic distributions between celiac and control children in Santiago, Chile.},
  author={Francisco P{\'e}rez-Bravo and Magdalena Araya and Alejandro Mondragon and Gloria V{\'e}liz R{\'i}os and Tatiana Alarc{\'o}n and Joerg Roessler and Jos{\'e} Luis Santos},
  journal={Human immunology},
  year={1999},
  volume={60 3},
  pages={
          262-7
        }
}
Celiac disease is a permanent gluten intolerance strongly associated with HLA class II antigens. The over presentation of particular HLA alleles and haplotypes has been described in several populations. Different lines of evidence obtained during the last years suggest that a particular HLA-DQ heterodimer, encoded by the DQA1*0501 and DQB1*0201 genes in cis or trans conformation, confers the primary disease susceptibility. We report the HLA class II allelic distribution and DQA1/ DQB1 genotypes… CONTINUE READING
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Genetic analysis of HLA DRB1, DQA1, and DQB1 HLA-DQA1* and DQB1* Allelic Distributions alleles and susceptibility to type I (insulin-dependent) diabetes mellitus

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