Genetic developments in autoimmune thyroid disease: an evolutionary process.

@article{Zeitlin2008GeneticDI,
  title={Genetic developments in autoimmune thyroid disease: an evolutionary process.},
  author={Abigail A Zeitlin and Matthew J. Simmonds and Stephen C. L. Gough},
  journal={Clinical endocrinology},
  year={2008},
  volume={68 5},
  pages={
          671-82
        }
}
The identification of genes placing individuals at an increased risk for the development of autoimmune thyroid disease (AITD) has been a slow process. However, over the last 20 years or so real progress has been made with the mapping of novel loci, via a number of different approaches. First, through the use of traditional immunological methods, Human Leucocyte Antigen (HLA)/Major Histocompatibility Complex (MHC) was the first gene region to be associated with AITD and consistent replications… CONTINUE READING
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