Genetic determination of heart and kidney weights studied using a set of recombinant inbred strains: the relationship to blood pressure.

@article{Kunes1990GeneticDO,
  title={Genetic determination of heart and kidney weights studied using a set of recombinant inbred strains: the relationship to blood pressure.},
  author={Jaroslav Kunes̆ and Vladim{\'i}r Křen and Premysl Klir and Josef Zicha and Michal Pravenec},
  journal={Journal of hypertension},
  year={1990},
  volume={8 12},
  pages={1091-5}
}
The effects of genetic factors and blood pressure levels on heart and kidney weights were estimated in a set of recombinant inbred (RI) strains obtained by crossing normotensive rat (BN.lx) and genetically hypertensive rat (SHR) progenitor strains. Renal or cardiac hypertrophy in several normotensive RI strains, together with low organ weights in some hypertensive strains, indicate that genetic factors play an important role in heart and kidney weight determination. In RI strains, there was a… CONTINUE READING

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