Genetic determinants of obesity-related lipid traits.

  title={Genetic determinants of obesity-related lipid traits.},
  author={Gabriele E. Sonnenberg and Glenn R. Krakower and Lisa J Martin and Michael Olivier and Anne E Kwitek and Anthony Gean Comuzzie and John Blangero and Ahmed H. Kissebah},
  journal={Journal of lipid research},
  volume={45 4},
In our ongoing effort to identify genes influencing the biological pathways that underlie the metabolic disturbances associated with obesity, we performed genome-wide scanning in 2,209 individuals distributed over 507 Caucasian families to localize quantitative trait loci (QTLs), which affect variation of plasma lipids. Pedigree-based analysis using a quantitative trait variance component linkage method that localized a QTL on chromosome 7q35-q36, which linked to variation in levels of plasma… CONTINUE READING


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P. Green, K. Falls, S. Crooks
Version 2.4. Department of Genetics, • 1990
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Highly Influenced

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